Daria… smiling in the not aired pilot episode.
Life in Hell was a weekly comic strip by Matt Groening, creator of The Simpsons and Futurama, which was published from 1977 to 2012. The strip featured anthropomorphic rabbits and a gay couple. Groening used these characters to explore a wide range of topics about love, sex, work, and death. His drawings were full of expressions of angst, social alienation, self-loathing, and fear of inevitable doom.